COMBINED ANALYSIS OF RRBS DNA METHYLOME AND TRANSCRIPTOME REVEAL NOVEL CANDIDATE GENES RELATED TO PORCINE CLOSTRIDIUM PERFRINGENS TYPE C-INDUCED DIARRHEA

Clostridium perfringens type C (Cp) is one of the principal microorganisms responsible for bacterial diarrhea in neonatal and pre-weaning piglets.To better understand the molecular effects of Cp infection, we performed a genome-wide comparison of the changes in DNA methylation and gene expression in Cp infected resistant and susceptible piglets.We

Chronic non-specific low back pain mega cell horse supplement (CNLBP) is one of the leading causes of disability worldwide.Acupoint embedding (ACE) is widely used in China for the treatment of chronic non-specific low back pain, but there are no rigorous randomized controlled trials (RCTs) to confirm the effectiveness and safety of ACE for chronic

Background: As global efforts to increase the nursing and midwifery workforce intensify to improve access and quality of healthcare, clinical nursing and midwifery research must increase concomitantly to provide a solid evidence base for these clinicians.To maximize research resources in resource-poor regions, the research team collaborated with re

Providing anesthesia to patients with myotonic dystrophy (DM) can be very challenging due to the multisystemic effects of the disease and extreme sensitivity of these patients to sedatives, opioids, and anesthetic agents.Other factors such as hypothermia, shivering, or mechanical or electric stimulation during surgery can precipitate myotonia which

In 2021, aware of both the importance of pan-Canadian data access for advancing health research and the conditions and requirements that make administrative data access onerous, HDRN copyright worked with CATCO the Canadian arm of an international COVID-19 clinical trial to create a roadmap for navigating the barriers to multi-regional administrati